Evaluation of Locally Established Reference Intervals for Hematology and Biochemistry Parameters in Western Kenya

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Evaluation of Locally Established Reference Intervals for Hematology and Biochemistry Parameters in Western Kenya

BACKGROUND Important differences have been demonstrated in laboratory parameters from healthy persons in different geographical regions and populations, mostly driven by a combination of genetic, demographic, nutritional, and environmental factors. Despite this, European and North American derived laboratory reference intervals are used in African countries for patient management, clinical tria...

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Reference intervals for biochemistry parameters for evaluation of oxidative stress in human sperm.

References 1. Plebani M, Carraro P. Mistakes in a stat laboratory: types and frequency. Clin Chem 1997;43:1348–51. 2. Stuart J, Banfi G, Deom A, Narayanan S, Rabinovitch A. Major themes of the symposium. In: Proceedings of the second symposium: the impact of the pre-analytical phase of laboratory result. Oxford, UK: Becton Dickinson, 1996:5–9. 3. Hinckley CM. Defining the best quality-control s...

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CLSI-Derived Hematology and Biochemistry Reference Intervals for Healthy Adults in Eastern and Southern Africa

BACKGROUND Clinical laboratory reference intervals have not been established in many African countries, and non-local intervals are commonly used in clinical trials to screen and monitor adverse events (AEs) among African participants. Using laboratory reference intervals derived from other populations excludes potential trial volunteers in Africa and makes AE assessment challenging. The object...

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The Evaluation of Error Types and Turnaround Time of Preanalytical Phase in Biochemistry and Hematology Laboratories

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BACKGROUND There are 8 species of Pangolins found in Asia and Africa. Among them, the Chinese Pangolin (Manis pentadactyla) is an endangered insectivorous mammal found only in Asia. Hematology and serum chemistry reference intervals are critical for evaluating an animal's well-being and can be useful for clinical diagnostic purposes. Currently, there are no such reference intervals available fo...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2015

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0123140